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Juan-Carlos Hernández-Boluda Selected Research

Imatinib Mesylate (Gleevec)

2/2012Functional polymorphisms in SOCS1 and PTPN22 genes correlate with the response to imatinib treatment in newly diagnosed chronic-phase chronic myeloid leukemia.
8/2011Correlation between genetic polymorphisms of the hOCT1 and MDR1 genes and the response to imatinib in patients newly diagnosed with chronic-phase chronic myeloid leukemia.
8/2010Early intervention during imatinib therapy in patients with newly diagnosed chronic-phase chronic myeloid leukemia: a study of the Spanish PETHEMA group.
7/2010XPC genetic polymorphisms correlate with the response to imatinib treatment in patients with chronic phase chronic myeloid leukemia.
4/2009Sustained complete molecular remission after imatinib discontinuation due to severe aplastic anemia.
10/2003Imatinib mesylate therapy of chronic phase chronic myeloid leukemia resistant or intolerant to interferon: results and prognostic factors for response and progression-free survival in 150 patients.

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Juan-Carlos Hernández-Boluda Research Topics

Disease

8Primary Myelofibrosis (Myelosclerosis)
01/2022 - 11/2004
7BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
02/2012 - 01/2002
4Neoplasms (Cancer)
06/2022 - 05/2012
3Venous Thrombosis (Deep-Vein Thrombosis)
11/2022 - 08/2010
3Hemorrhage
11/2022 - 08/2010
3Anemia
04/2017 - 11/2015
3Thrombosis (Thrombus)
06/2015 - 08/2010
1Infections
01/2019
1Thrombocytopenia (Thrombopenia)
01/2016
1Rupture
11/2015
1Leukemia
09/2014
1Philadelphia Chromosome
09/2014
1Polycythemia Vera
02/2012
1Essential Thrombocythemia
08/2010
1Genomic Instability
07/2010
1Aplastic Anemia (Anemia, Hypoplastic)
04/2009
1Neutropenia
10/2003
1Exanthema (Rash)
02/2003
1Muscle Cramp (Cramp)
02/2003

Drug/Important Bio-Agent (IBA)

6Imatinib Mesylate (Gleevec)FDA Link
02/2012 - 10/2003
3Proteins (Proteins, Gene)FDA Link
08/2011 - 07/2006
2ErythropoietinFDA Link
04/2017 - 11/2004
2Phosphotransferases (Kinase)IBA
09/2014 - 07/2010
1CoagulantsIBA
11/2022
1Immunomodulating AgentsIBA
11/2022
1HematinicsIBA
04/2017
1Prednisone (Sone)FDA LinkGeneric
01/2016
1Danazol (Azol)FDA LinkGeneric
11/2015
1Vitamin KFDA Link
06/2015
1ponatinibIBA
09/2014
1Tyrosine Kinase InhibitorsIBA
09/2014
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
06/2013
1Codon (Codons)IBA
05/2012
1Hydroxyurea (Hydrea)FDA LinkGeneric
02/2012
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
08/2010
1insulin receptor-related receptor (IRR)IBA
08/2010
1SurvivinIBA
05/2005
1InterferonsIBA
10/2003
1EnzymesIBA
02/2003
1Interferon-alpha (Interferon Alfa)IBA
01/2002
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2002

Therapy/Procedure

8Therapeutics
04/2017 - 10/2003
4Cell Transplantation
06/2022 - 12/2020
1Transplantation
01/2022
1Hematopoietic Stem Cell Transplantation
01/2019
1Secondary Prevention
06/2015
1Stem Cell Transplantation
01/2002